Formulation and evaluation of carvedilol melt-in-mouth tablet using mucoadhesive polymer and PEG-6-stearate as hydrophilic waxy binder
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چکیده
منابع مشابه
Formulation and Evaluation of Mucoadhesive Buccal Tablet of Simvastatin
In present study mucoadhesive buccal tablet of simvastatin was prepared. Solubility of Simvastatin was enhanced by complexing Simvastatin with β-CD in 1:2 molar concentrations. Six different formulations of tablets of Simvastatin containing the polymers in various combinations were prepared by direct compression method and characterized for swelling studies, % matrix erosion, surface pH, mucoad...
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متن کاملNano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet.
PURPOSE In the present study rapid melt tablets (RMT's) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism. METHODS The spray-dried microparticles were formulated into RMT's using a wet granulation process. The Formulat...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Investigation
سال: 2012
ISSN: 2230-973X
DOI: 10.4103/2230-973x.106989